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1 Raindrops Keep Falling on My Head 2 Enough is Enough (No More Tears) 3 Make Me Lose Control 4 Deny Deny Deny 5 Bring the Pain 6 Into You Like a Train 7 Something to Talk About 8 Let it Be 9 Thanks for the Memories 10 Much Too Much 11 Owner of a Lonely Heart 12 Grandma Got Run Over by a Reindeer 13 Begin the Begin 14 Tell Me Sweet Little Lies 15 Break on Through 16 It's the End of the World 17 (As We Know It) 18 Yesterday 19 What Have I Done to Deserve This? 20 Band-Aid Covers the Bullet Hole 21 Superstition 22 The Name of the Game 23 Blues for Sister Someone 24 Damage Case 25 17 Seconds 26 Deterioration of the Fight or Flight Response 27 Losing My Religion

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Ellis is admitted to the hospital. The secret is out -- Meredith's mom, the brilliant surgeon, has Alzheimer's. Cristina faints in Burke's surgery. Addison operates on Cristina who loses the baby and one of her fallopian tubes. Bailey is supportive of Cristina through her surgery and recovery. Burke is concerned for Cristina, but is kept busy in surgery. He finally discovers Cristina was pregnant. The interns sit at Cristina's bedside, after her surgery, but Burke can't bring himself to enter. Izzie and Alex are flirting with each other. Izzie feels left out, always the last to know about everything -- especially when it comes to her friends. George reminds Ellis of Meredith's father. He defends Meredith to Ellis: I don't like the way you talk to her. Then later, he comforts Ellis by lying in bed with her, letting her think he's Thatcher.

  Female patients find Derek just as McDreamy as the staff -- as is the case with Derek's young patient who is in for surgery to make her stop blushing. Addison asks Derek to consult on a case of a premature baby in ICU, who has very little chance of surviving. Addison has hope, both for the baby, and for their marriage. She kisses Derek. Richard comes back to the hospital before Derek clears him for surgery. Derek is holding a grudge because Richard gave interim chief to Burke and invited Addison "Satan" to Seattle. Meredith tells Richard that Ellis is reliving the heyday of her residency and would appreciate a visit from him. Richard can't bring himself to go see Ellis. He tells George to take care of her. When Richard finally goes to Ellis' room, Ellis grabs Richard's hand: Richard, you beautiful man, thank God you're here. Meredith finally breaks down from having to pretend all day long that she is fine. She is tired of hating Derek. She can't do it anymore. Meredith kisses Derek.