Meredith: [voiceover] In general, lines are there for a reason: for security, for clarity. If you choose to cross the line, you pretty much do so at your own risk. So why is it, that the bigger the line, the greater the temptation to cross it?

George: My dad's a truck driver, my mom's a teacher. If the evening news shows me crossing a picket line, they'll outlive me just to pee on my grave.

Chief: We need an additional 40 nurses to relieve the overtime that they're striking about. That's 2 million dollars a year we don't have.

Derek: Have you checked under the couch? I always find spare change under the cushions.

Cristina: George is cowering behind the picket line like a little girl.

Sydney: Standing up for what he believes in, that's my kind of little girl! Am I right?

Sydney: [about Cristina, who wants to remove the patient's leg] And when I do, our eager young intern here can hold the saw. Unlike Dr. Karev, kindness and compassion aren't very high on her list of priorities, but a little bone-saw action? Maybe that will earn me some respect, am I right?

Izzie: [trying to convince a patient to give her child up for adoption] She can have more than a trailer park and a graveyard shift at a truck-stop diner. Don't you want that for her? I mean, if you can get past the fact that I'm superior, and that I'm judging you, and telling you what's best for your family...if you can just get past all of that, isn't it possible that I'm also right?

Cristina: I'm not used to being wrong.

Burke: I know. But you're an intern. Second-guessing a resident? That's not your job.

Cristina: Excuse me, why aren't YOU apologizing?

Burke: I'm an Attending, I don't have to apologize to residents. You, on the other hand, are an intern.

George: [after Meredith and Izzie climb into his bed] What happened today?

Izzie: Nothing.

Meredith: Nothing.

George: Okay.

Izzie: We don’t know everything about each other, George.

Meredith: Yeah.

George: True … anybody want to have sex?

Meredith: [voiceover] We can’t help ourselves. We see a line, we want to cross it. Maybe it’s the thrill of trading the familiar for the unfamiliar. A sort of personal dare. Only problem is, once you’ve crossed it’s almost impossible to go back. But if you do manage to make it back across that line you find safety in numbers.