Derek and
Richard wait outside for a special patient with a serious problem.
Archer Montgomery, world famous neurologist and brother to our very own
Addison Montgomery is suffering from continuous, unrelenting, dangerous
seizures. Addison, unwilling to believe her brother's condition is
fatal had Archer airlifted to Seattle Grace and has asked Derek to save
him. Archer's got neurocystercercosis or parasites in his brain. Is it
too late for Derek to help him?
Unlike the common cold, neurocystercercosis isn't an air born
infection, it is a fecal, oral disease, meaning it's shed in the bowel
movements of a host and must be ingested by a new host in order to
cause an infection. When Archer visited Mexico, he ate unwashed fresh
fruit. Unfortunately, crops from undeveloped countries are often
irrigated with water with fecal contamination and Archer ate tapeworm
larvae.
The larvae traveled to the intestines where it hatched. Then were
absorbed into the bloodstream. They traveled through the circulatory
system where they were able to penetrate the not-easy-to-get-through
blood-brain barrier and arrived in the brain. Here, they found a good
place to live, the third ventricle.
The third ventricle is located deep, deep in the brain, between the two
hemispheres. It's chamber with a constant flow of cerebral spinal fluid
(CSF) flowing through it. It's very important that the stream remain
flowing, because there's nowhere to store excess CSF fluid. If there is
a back-up of the fluid, the third ventricle swells, putting pressure on
the brain stem, which controls basic functions like breathing and the
heartbeat.
There's no easy way to get to the third ventricle, which is why Archer
has been adamantly against surgery. Derek concurs, at first...
As Derek looks at the pictures of Archer's affliction he formulates a
plan. If Derek were to use an endoscope, he could thread a small tube
through the brain into the third ventricle and feed the necessary tools
through this tube. He will need something to pierce the cysts and a
vacuum instrument to remove the fluid and the worm quickly. If he does
this one by one, there is a chance he could remove all of the cysts and
all of the worms living in them, waiting to hatch.
Just as Derek is about to finish the surgery, one of the cysts bursts
and a tiny little worm escapes and swims through the ventricle,
blocking the hole that the CSF drains from. This causes Archer to go
into cardiac arrest (or to code). The natural instinct of everyone in
the OR is to resuscitate Archer's heart, but, unless Derek can relieve
the pressure that the buildup of CSF fluid is putting on the brain
stem, they will not be able to start the heart. If Derek can't capture
that worm, no amount of shocking Archer's heart is going to bring him
back. Luckily Derek knows this. He quiets everyone and focuses. Sure
enough, Derek is able to catch the renegade worm and Archer's heart
begins to beat, just like Derek said it would.