Dream a Little Dream of Me 3 Here Comes the Flood 4 Brave New World 5 There's No 'I' in Team 6 Life During Wartime 7 Rise Up 8 These Ties That Bind 9 In the Midnight Hour 10 All By Myself 11 Wish You Were Here 12 Sympathy for the Devil 13 Stairway to Heaven 14 Beat Your Heart Out 15 Before and After 16 An Honest Mistake 17 I Will Follow You Into the Dark 18 Stand By Me 19 Elevator Love Letter 20 Sweet Surrender 21 No Good at Saying Sorry 22 Beautiful Day 23 Here's to Future Days

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Meredith: [narrating] Every surgeon has a shadow. And the only way to get rid of a shadow,is to turn off the light. To stop running from the darkness, and face what you fear. Head on.

Meredith: I know there's a ring.
Derek: What?
Meredith: The Chief told me. I know there's a ring.
Derek: You want the ring? Here's your ring. (Smacks it with his baseball bat into the distance, throws the bat on the ground and walks into the trailer)
Meredith: Is that the best you've got? 'Cause I'm not bailing, we're in this together.
Derek: GO HOME MEREDITH!

Meredith: DEREK SHEPHERD YOU ARE DRUNK! And you're angry, and I've been there so I get it. But that does not give you the right...
Derek: Just go home Meredith.
Meredith: You don't get to just stand here and tell me.
Derek: This is what you want, I'm giving you an out. Go.
Meredith: I'm not going anywhere.
Derek: I SAID LEAVE! MEREDITH, LEAVE!

Meredith: Oh, Ok. So you're just quitting?
Derek: You should understand better than anybody else. You wrote the book on quitting. Running, hiding, you've written a lot of books Meredith.
Meredith: That may be true. But I'm here now.
Derek: Oh, hmm, you're here now? Haha. You've wanted me out since the day I moved in.
Meredith: That is not true.
Derek: Because you're incapable of anything that resembles commitment. You lied to me, you said you were healthy. That you were healed. There's no fixing you, you're a lemon.

Meredith: You cleaned all of your clothes out of the closet at the house.
Derek: Go home Mer. Just go home.
Meredith: Well, how long are you planning on hiding out here? Because that's what you're doing. You're hiding. You made a mistake, she's dead and you can't hide from that.
Derek: I'm not hiding. I'm done. I'm done operating.

Lexie: Yes, the odds are against us. I'm a one woman wrecking ball, all I do is break you. Your hand, your penis, your relationships, your life. I'd say our survival rate is about 3 percent. And that's, that's, that's bad. But, it's not nothing. And I don't think we should give up on this. At least not yet because...
Mark: (puts finger to Lexie's lips)
Lexie: Okay.
Mark: You think you broke me little Grey? You're the one that put me back together.

Richard: I know I have no business asking you for anything, but I need your help. I need you to bring Derek back. And he's not fine.
Meredith: Sometimes people just wanna be left alone.
Richard: He's planning to propose. He's been carrying around a big ring for weeks. That's not a man who wants to be left alone. I just thought you should know.

Owen: What are you doing?
Cristina: Assigning myself to a trauma with you tomorrow.
Owen: Cristina.
Cristina: You know, I'm a big girl. I can handle my share of trauma, and I get to decide when I've had enough. It's gonna take a lot more than a bad dream to scare me off.
Owen: It's more than a bad dream.
Cristina: I know.

Alex: I know you like teaching and that's great, but you need to start treating real patients, with real surgeries. Because once they see you as weak, it's over. And Izz, you can be a great surgeon. We could be great together. You just, you gotta stop screwing around. Because I don't wanna be the future of this hospital if you're not there with me. Okay?
Izzie: Okay.
Alex: (walks away)
Izzie: ALEX!
Alex: What?
Izzie: (kisses him)

Alex: Iz! They said I could do the distal anastomosis on my own.
Izzie: That's awesome!
Alex: That's crazy. They just told me I could be the future of this hospital. That I'm the resident to watch. And that's... I mean... I'm not the kinda guy who. I don't rise okay, I sink to the bottom. And now I'm getting all this, all this respect. And you... you gotta, you gotta stop wasting all your time with this patient X crap.

Lexie: I learned a lot today. Diagnosing a patient from beginning to end. So, thank you for teaching us.
Izzie: What would you say? To patient X. How would you... How would you break the news?
Lexie: Um, I would say that I was very sorry, and that there were support groups. Th... I ... I don't know. What do you say to somebody whose, whose gonna...
Izzie: You say, they have a choice. They can runaway and hide from it, or they can face it. You say they need to be around the people who love them, because it's gonna be the toughest fight of their life, and no one should have to do it alone. And then you give them the odds. And even though a 5 percent survival rate is bad, it's really bad. You say.... you say....
Lexie: Screw the odds! People die of the hiccups. My mother died of the hiccups. Survival rate for that is what... 100 percent? The odds are that she should be alive right now. The odds are... The odds are crap! So people should face it and they should fight. Maybe not those words.
Izzie: No. Exactly those words. Thank you doctor Grey.

Izzie: Good job everybody.
Intern: That's it?
Intern: After the last contest, we got a prize.
Intern: Yeah, what's our prize?
Izzie: You think every time you diagnose a patient and hand someone a death sentence, there's a prize? The prize is, you didn't screw it up this time. The prize is, you people actually did something right. The prize is, you were doctors today. You were doctors. That is the prize!

Lexie: We have a diagnosis.
Izzie: Go ahead doctor Grey.
Lexie: Patient X. An elevated LDH was our only clue. And then we found out that she had enlarged lymph nodes, and a suspicious mole which was biopsied. Meanwhile, this MRI with contrasts showed a MET on her right temporal lobe. The biopsy reveled dividing cells. That coupled with further staging tests, lead to our final diagnosis of Metastatic Melanoma, with MET's to the liver, skin and brain.
Izzie: Your prognosis?
Lexie: With chemo, and radiation, um, a few months.
Intern: At best, girls pretty much toast.
Intern: Survival rate's 5 percent. If I were her, I'd go on a really good vacation.

Izzie: You read more journals and do more research, and log more hours in the skills lab than any other resident here. You never give up on trying to be a better doctor, and you don't step on other people to do it. I would be lucky to be the new you.
George: Are you gonna tell me about patient X?

Izzie: Maybe Cristina's right. Maybe trying to teach the interns is pointless.
George: Please, don't listen to Cristina. She thinks just because you'd rather teach then take out a gall bladder that you're the new me.
Izzie: Haha, O'Malley the sequel.
George: O'Malley 2.0.

Lexie: Ok well her SED rate is slightly elevated. Do we check for auto-immune disease?
Intern: Yeah, ANA and CRP were negative too. At worst she's got an anxiety disorder. The girl is totally fine!
Izzie: SHE IS NOT FINE! She had hallucinations. She had visual, auditory and tactile hallucinations about her dead fiance. She thought she could talk to him, and touch him. She's not fine. She's not fine. You're missing something. You're not looking in the right places. Go back and figure out what you're missing.

Intern: Woah woah, wait wait. Liver enzymes are normal. Cardiac work up is negative.
Intern:If LDH is false positive.
Intern: It's a trick question!
Izzie: What?
Intern: She's fine. Patient X is fine.
Izzie: She's not fine.

Cristina: See it's not emotional, it's science. You have a problem, don't ignore it.
Meredith: Well, sometimes if you have to pee and you ignore it, it does go away.
Izzie: Haha, you guys are hilarious! I mean do you even know what she just said? Or what she just said? I can totally see you guys in 50 years, at a nursing home, just talking at each other with your hearing aids off. Hahaha! HI-LARIOUS! Ah, I love lunch.
 
Meredith: Oh my god! I'm the strong one.
Cristina: You see, if I had that stomach cancer gene, I would get that gastrorectomy no problem. I face things, I don't walk away.
Meredith: Derek walks away. Maybe walking away is the answer?

Meredith: He had to get all scalpel happy up in that patients brain, and now he can't face it!
Cristina: He thinks I'm what? This wilting flower? Well guess what, I'm the strong one.

Meredith: And he just walked out. Without saying a word, he just walked out!
Cristina: Hunt won't even look at me, since he went all apocalypse now on me this morning.

Derek: I'M NOT OPERATING!
Richard: I'M NOT ASKING, I'M TELLING! AS CHIEF SURGEON OF THIS HOSPITAL, IF YOU DON'T GET BACK IN THAT OR TODAY SHEPHERD ...

Richard: Oh, Shepherd! Thank god your back. Can you swing two brain biopsies today?
Derek: I'm not operating.
Richard: Look, I know you've got a big law suit breathing down your neck, and I know you lost a patient. But, I need you back to work doing the job I hired you to do.

Meredith: You're not looking at the big picture.
Derek: This is the big picture.

Meredith: How'd it go with the lawyers?
Derek: They told me my death rate. (looks at small pile) These are the people I saved. (looks at big pile) These are the people I killed.
Meredith: Okay. Well most of those people were terminal when they came to you. You were their last chance, and you take on impossible cases. Look at the clinical trial.
Derek: It's just so many people. More than Domer, Adson, and Bundy combined.

Mark: Have you heard of a... Doctor Nelson in Neuro?
Callie: Oh yeah. Haha, shadow Shepherd.
Mark: Shadow Shepherd?
Callie: Yeah, he's a solid surgeon, but sort of the JV player to Shepherd's Varsity. The B team to Shepherd's A. The brick layer to Shepherd's architect.
Mark: I get it! Just 'cause a guy doesn't publish fancy clinical trials, or takes on flashy surgeries, or has creepy perfect hair, he's less of a man?
Callie: Kinda.

Callie: You realize that as your doctor I'm not recommending this right?
Mark: I need to get through my surgeries today.
Callie: Oh you're gonna get through them. You're just gonna be in a world of hurt later.

Meredith: What's this patient X thing that's taking all the interns?
Cristina: Yeah, and when's it gonna be over? I need minions to do my crap work!
Alex: It's some new teaching thing.
Cristina: We're all killing ourselves to get into the OR. When's the last time Izzie held a scalpel? She's falling behind. She's like the new O'Malley.
Alex: Izzie's nothing like O'Malley.
George: Hello?

Izzie: Look at you, with your stethoscope around your neck. Charting. I can totally see you in 10 years. A little salt and pepper in your hair, a big shot attending. You're gonna be a rock star Alex.
Alex: What is this?
Izzie: What? I can't fantasize about my boyfriend and his bright, bright future?
Alex: Shut up.

Lexie: HI!
Mark: HAND!
Lexie: Hand! Oh god! I'm sorry! I forgot. I'm so sorry. I feel terrible, about everything. About the fight, and your hand, and Derek. You know he's not doing so well, I really think that you should talk to him.
Mark: I should talk to him?
Lexie: Mhmm.

Mark: What are you doing?
Callie: I went all... say anything on the peades surgeon, in front of the peds surgeons date. So now I am hiding from the peades surgeon.
Mark: Hm, mature.
Callie: Um, you got in a fist fight. No judging!

Callie: It's still swollen. I'd give it another day of rest.
Mark: I haven't operated in 3 days!
Callie: Don't hit people with your scalpel hand. Have you talked to him yet?
Mark: He threw the first punch.
Callie: You did catch him at a bad time.
Mark: So he lost a patient. Boo hoo! We're surgeons. We're men. We lose patients. It doesn't give him the right to go around behaving like a drunk frat boy. Now I'm supposed to go crawling back begging for his forgiveness?

Meredith: There you are. What happened to you?
Cristina: I tripped and fell. It's fine.
Owen: No, it's not!
Cristina: It's nothing. It was an accident. What's wrong with you?
Meredith: Ah, Derek won't get off the couch.
Cristina: SO the weaker sex!

Cristina: I dreamt once that I was falling out a window, hanging onto the drapes. I woke up, pulling Meredith's hair out. HAH!
 
Meredith: Hey, so you're eating. That's good. Appetite is good. You know what else is good? Showering. Cleansing. Water. Are you thinking you'll shower? Maybe go into the hospital?
Derek: I have to for the deposition. I have to go and explain in detail how I killed a man's pregnant wife.
Meredith: That's good. I mean, not the killing part, but the... I... I think you'll feel better once you... go to... work.
(Derek walks over and shoves the cereal box into Alex's hands, and storms off)
Meredith: He'll be fine.
 
Alex: Dude, he is fried.
Meredith: He is not fried. He lost a patient, and got hit with a law suit all in one week. He just needs time.
Alex: He's been sitting there for 3 days. The sofa cushions are gonna start bonding to his ass, and he's eating all my cereal.
Izzie: He's taking stock. Something huge and life altering happened to him and he's taking stock. Figuring out his next move. We shouldn't judge him, we shouldn't rush him.
Alex: Whatever. Sylvia Plath's picking out all the marshmallows. Their the best part!
Lexie: And I'm pretty sure he's sitting on my keys. I'd ask him to move, but he looks so comfy.
Meredith: You guys are cowards!

Meredith: [narrating] Every surgeon I know, has a shadow. A dark cloud of fear and doubt, that follows even the best of us into the OR. We pretend the shadow isn't there. Hoping that if we save more lives, master harder techniques, run faster and farther, it'll get tired and give up the chase. But, like they say, you can't outrun your shadow.